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Figure 6. Enrichment of H3K4me3 at inactive genes occurs in differentiated cells.
A,C,E,G. Composite enrichment profiles for H3K4me3 (A,C) and Pol II (E,G) enrichment in primary human hepatocytes (A, E) and REH line of proB-cells (C, G) at genes called present or absent for mRNA transcript using microarray data as in Figure 2G.
B,D,F,H. Enriched probes (blue) and unenriched probes (white) profiles for H3K4me3 (B,D) and Pol II (F,H) are shown for each gene in hepatocytes (B,F) and B-cells (D,H). Individual genes are represented top to bottom and ordered by average binding ratio within 1kb surrounding transcription start sites as in Figure 1D.