DNA Microarray

Genome-wide Expression Analysis


The transcriptional regulatory circuitry of yeast and human cells is being deduced through the use of high density oligonucleotide arrays. We are exploring the role of the transcription apparatus, chromatin and signaling pathways in regulation of genome expression.


Transcripton apparatus:


Environmental Changes:

Signal Transduction:




Macrophage Infection by Bacterial Pathogens:

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