Nucleosome-dependent Gene Expression and Silencing in Yeast

  

We are using genome-wide expression analysis to understand the effects of chromatin components on gene regulation. This site supports Wyrick, et al., Nature 402:418-421 (1999).


Study Design

 

Project Goals
Genetic Reagents
Technology
Protocols
Analysis
  

Gene Expression Data

 

Histone Depletion
RAP1
SIR2
SIR3
SIR4
  

Chromosome Display

  

Histone Depletion
RAP1
SIR2
SIR3
SIR4
  

Results and Insights

  

Summary
Additional Issues and Analysis
Statistical Analysis
Positive and Negative Effects
Telomere-Proximal Genes
Telomere Silencing
Control Data Sets
  


Acknowledgements
Glossary
References
Links

Nature

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